<\/p>\n\n\n\n
\u039f \u03ac\u03be\u03bf\u03bd\u03b1\u03c2 \u03ad\u03bd\u03c4\u03b5\u03c1\u03bf\u2013\u03ba\u03b1\u03c1\u03b4\u03b9\u03ac (gut\u2013heart axis) \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c0\u03b5\u03b4\u03af\u03bf \u03c1\u03b1\u03b3\u03b4\u03b1\u03af\u03b1\u03c2 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1\u03c2 \u03c4\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1. \u03a0\u03bb\u03ad\u03bf\u03bd \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03bf\u03c5\u03bc\u03b5 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03b4\u03b5\u03bd \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03bc\u03cc\u03bd\u03bf \u03c4\u03b7 \u03b3\u03b1\u03c3\u03c4\u03c1\u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03ae \u03c5\u03b3\u03b5\u03af\u03b1, \u03b1\u03bb\u03bb\u03ac \u03b4\u03b9\u03b1\u03b4\u03c1\u03b1\u03bc\u03b1\u03c4\u03af\u03b6\u03b5\u03b9 \u03ba\u03c1\u03af\u03c3\u03b9\u03bc\u03bf \u03c1\u03cc\u03bb\u03bf \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03bf\u03b4\u03bf \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ce\u03bd \u03bd\u03bf\u03c3\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd \u2014 \u03cc\u03c0\u03c9\u03c2 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7, \u03b1\u03b8\u03b7\u03c1\u03bf\u03c3\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7, \u03c3\u03c4\u03b5\u03c6\u03b1\u03bd\u03b9\u03b1\u03af\u03b1 \u03bd\u03cc\u03c3\u03bf\u03c2 \u2014 \u03ba\u03b1\u03b9 \u03b5\u03c0\u03b7\u03c1\u03b5\u03ac\u03b6\u03b5\u03b9 \u03c4\u03b7\u03bd \u03ad\u03ba\u03b2\u03b1\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03bf\u03be\u03cd \u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1 \u03bc\u03c5\u03bf\u03ba\u03b1\u03c1\u03b4\u03af\u03bf\u03c5 (MI).<\/p>\n\n\n\n
1.1 \u03a5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7, \u03b1\u03b8\u03b7\u03c1\u03bf\u03c3\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b5\u03c6\u03b1\u03bd\u03b9\u03b1\u03af\u03b1 \u03bd\u03cc\u03c3\u03bf\u03c2<\/strong><\/p>\n\n\n\n \u03a0\u03bf\u03bb\u03bb\u03ad\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b4\u03b5\u03af\u03c7\u03bd\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7 \u03ad\u03c7\u03bf\u03c5\u03bd \u03bc\u03b5\u03b9\u03c9\u03bc\u03ad\u03bd\u03b7 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03cc\u03c4\u03b7\u03c4\u03b1 (\u03b1-diversity) \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03b9\u03b1\u03ba\u03ac \u03b5\u03af\u03b4\u03b7 \u03c3\u03b5 \u03c3\u03c7\u03ad\u03c3\u03b7 \u03bc\u03b5 \u03c5\u03b3\u03b9\u03b5\u03af\u03c2. 1.2 \u039a\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf \u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1<\/strong><\/p>\n\n\n\n \u03a3\u03b5 \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03cc \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03bf (\u03c0\u03bf\u03bd\u03c4\u03af\u03ba\u03b9\u03b1 \u03bc\u03b5 \u03c5\u03c0\u03b5\u03c1\u03c4\u03b1\u03c3\u03b9\u03ba\u03ae \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1), \u03b7 \u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c4\u03bf\u03c5 \u03bb\u03cc\u03b3\u03bf\u03c5 Firmicutes\/Bacteroidetes, \u03bc\u03b5 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03bf\u03b9\u03ba\u03bf\u03b3\u03b5\u03bd\u03b5\u03b9\u03ce\u03bd \u03cc\u03c0\u03c9\u03c2 Lactobacillaceae, Lachnospiraceae, \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03c5\u03bd SCFAs. \u03a0\u03b1\u03c1\u03ac\u03bb\u03bb\u03b7\u03bb\u03b1, \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c4\u03ce\u03bd \u03cc\u03c0\u03c9\u03c2 SCFAs \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 TMAO \u03bc\u03b5\u03c4\u03b1\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03c5\u03c4\u03cc \u03c4\u03bf \u03bc\u03bf\u03bd\u03c4\u03ad\u03bb\u03bf, \u03c5\u03c0\u03bf\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03cc\u03c4\u03b9 \u03b7 \u03b4\u03c5\u03c3\u03b2\u03af\u03c9\u03c3\u03b7 \u03b4\u03b5\u03bd \u03b5\u03af\u03bd\u03b1\u03b9 \u03bc\u03cc\u03bd\u03bf \u03b1\u03bb\u03bb\u03b1\u03b3\u03ae \u03c3\u03c4\u03b7 \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03b1\u03bb\u03bb\u03ac \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u03c4\u03bf\u03c5 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03ce\u03bc\u03b1\u03c4\u03bf\u03c2. \u0397 \u03b1\u03bd\u03b1\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7 \u03c3\u03c4\u03bf Current Hypertension Reports \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c3\u03c5\u03c7\u03bd\u03ac \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03c5\u03bd butyrate \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1, \u03c3\u03c5\u03bc\u03b2\u03ac\u03bb\u03bb\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c3\u03c4\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03ba\u03b1\u03b9 \u03c3\u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd \u03c6\u03c1\u03b1\u03b3\u03bc\u03bf\u03cd. TMAO: \u03a0\u03c1\u03bf\u03ca\u03cc\u03bd \u03c4\u03b7\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bc\u03b5\u03c4\u03b1\u03c4\u03c1\u03bf\u03c0\u03ae\u03c2 \u03c4\u03b7\u03c2 \u03c7\u03bf\u03bb\u03af\u03bd\u03b7\u03c2 \u03ba\u03b1\u03b9 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c1\u03bd\u03b9\u03c4\u03af\u03bd\u03b7\u03c2. \u0391\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03b8\u03b7\u03c1\u03bf\u03c3\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7, \u03b8\u03c1\u03b1\u03cd\u03c3\u03b5\u03b9\u03c2 \u03c0\u03bb\u03b1\u03ba\u03ce\u03bd, \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b1\u03b9\u03bc\u03bf\u03c0\u03b5\u03c4\u03b1\u03bb\u03af\u03c9\u03bd, \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c4\u03ac \u03c3\u03c5\u03bd\u03ad\u03c0\u03b5\u03b9\u03b1 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf. SCFAs (\u03c0.\u03c7., \u03b2\u03bf\u03c5\u03c4\u03c5\u03c1\u03b9\u03ba\u03cc, \u03c0\u03c1\u03bf\u03c0\u03b9\u03bf\u03bd\u03b9\u03ba\u03cc, \u03bf\u03be\u03b9\u03ba\u03cc): \u03a0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1 \u03ba\u03b1\u03c4\u03ac \u03c4\u03b7 \u03b6\u03cd\u03bc\u03c9\u03c3\u03b7 \u03c6\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03b9\u03bd\u03ce\u03bd. \u0388\u03c7\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03ae \u03b4\u03c1\u03ac\u03c3\u03b7 \u2014 \u03c1\u03c5\u03b8\u03bc\u03af\u03b6\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c0\u03af\u03b5\u03c3\u03b7, \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03c5\u03bd \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03ba\u03b1\u03b9 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03bd\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03bd\u03b4\u03bf\u03b8\u03b7\u03bb\u03b9\u03b1\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1. \u0386\u03bb\u03bb\u03bf\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b5\u03c2: \u03a7\u03bf\u03bb\u03b9\u03ba\u03ac \u03bf\u03be\u03ad\u03b1, \u03b1\u03bc\u03b9\u03bd\u03bf\u03be\u03ad\u03b1 \u03b4\u03b9\u03b1\u03ba\u03bb\u03b1\u03b4\u03b9\u03c3\u03bc\u03ad\u03bd\u03b7\u03c2 \u03b1\u03bb\u03cd\u03c3\u03bf\u03c5 (BCAA) \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03bf\u03cd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03bf\u03cd \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03c0\u03c9\u03c2 \u03b5\u03bc\u03c0\u03bb\u03ad\u03ba\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b7\u03bd \u03c0\u03b1\u03b8\u03bf\u03c6\u03c5\u03c3\u03b9\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ce\u03bd \u03bd\u03cc\u03c3\u03c9\u03bd. 3.1 \u03a0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ac<\/strong><\/p>\n\n\n\n \u03a0\u03b1\u03c1\u03ac \u03c4\u03bf \u03b3\u03b5\u03b3\u03bf\u03bd\u03cc\u03c2 \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03c0\u03b5\u03c1\u03b9\u03c3\u03c3\u03cc\u03c4\u03b5\u03c1\u03b5\u03c2 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b5\u03c2 \u03b5\u03c0\u03b9\u03ba\u03b5\u03bd\u03c4\u03c1\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b1\u03c0\u03bf\u03ba\u03b1\u03c4\u03ac\u03c3\u03c4\u03b1\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac \u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1 \u03ae \u03c3\u03b5 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1, \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b1\u03c5\u03be\u03b1\u03bd\u03cc\u03bc\u03b5\u03bd\u03bf \u03b5\u03bd\u03b4\u03b9\u03b1\u03c6\u03ad\u03c1\u03bf\u03bd \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03c9\u03c2 \u03c0\u03c1\u03bf\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03ae \u03c0\u03b1\u03c1\u03ad\u03bc\u03b2\u03b1\u03c3\u03b7 \u03c3\u03c4\u03bf\u03c5\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03ba\u03b9\u03bd\u03b4\u03cd\u03bd\u03bf\u03c5 (\u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7, \u03b1\u03b8\u03b7\u03c1\u03bf\u03c3\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7). \u0391\u03bd\u03b1\u03c3\u03ba\u03bf\u03c0\u03ae\u03c3\u03b5\u03b9\u03c2 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03b6\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ac \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03c6\u03c1\u03b1\u03b3\u03bc\u03cc, \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03bf\u03c5\u03bd \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c4\u03c1\u03bf\u03c0\u03bf\u03c0\u03bf\u03b9\u03ae\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae TMAO. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03bc\u03b5 \u03c3\u03c4\u03cc\u03c7\u03bf \u03c4\u03b7\u03bd \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 SCFA \u03ae \u03c4\u03b7\u03bd \u03ba\u03b1\u03c4\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae \u03c4\u03b7\u03c2 TMA-\u03bf\u03b4\u03bf\u03cd \u03b5\u03af\u03bd\u03b1\u03b9 \u03c5\u03c0\u03cc \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03c9\u03c2 \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ae \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bd\u03cc\u03c3\u03bf\u03c5.<\/p>\n\n\n\n \u0397 \u03b5\u03c1\u03b5\u03c5\u03bd\u03b7\u03c4\u03b9\u03ba\u03ae \u03b5\u03c3\u03c4\u03af\u03b1\u03c3\u03b7 \u03c3\u03c4\u03bf \u03b2\u03bf\u03c5\u03c4\u03c5\u03c1\u03b9\u03ba\u03cc \u03bf\u03be\u03cd \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ac \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03c0\u03c1\u03bf\u03c4\u03ac\u03c3\u03c3\u03b5\u03b9 \u03c4\u03b7 \u03b4\u03c5\u03bd\u03b1\u03c4\u03cc\u03c4\u03b7\u03c4\u03b1 \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7\u03c2 “\u03ad\u03c4\u03bf\u03b9\u03bc\u03c9\u03bd” \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ce\u03bd \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c4\u03ce\u03bd, \u03c7\u03c9\u03c1\u03af\u03c2 \u03bd\u03b1 \u03c7\u03c1\u03b5\u03b9\u03ac\u03b6\u03b5\u03c4\u03b1\u03b9 \u03b7 \u03b5\u03c0\u03b9\u03b2\u03af\u03c9\u03c3\u03b7 \u03c4\u03c9\u03bd \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03c3\u03c4\u03bf \u03ad\u03bd\u03c4\u03b5\u03c1\u03bf.<\/strong><\/p>\n\n\n\n \u03a4\u03b1 SCFAs \u03cc\u03c0\u03c9\u03c2 \u03c4\u03bf \u03b2\u03bf\u03c5\u03c4\u03c5\u03c1\u03b9\u03ba\u03cc \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03b4\u03c1\u03ac\u03c3\u03bf\u03c5\u03bd \u03c9\u03c2 \u201c\u03b1\u03bd\u03bf\u03c3\u03bf\u03c1\u03c1\u03c5\u03b8\u03bc\u03b9\u03c3\u03c4\u03b9\u03ba\u03ac \u03bc\u03cc\u03c1\u03b9\u03b1\u201d, \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03bf\u03c5\u03bd \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03b2\u03b5\u03bb\u03c4\u03b9\u03ce\u03c3\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b5\u03bd\u03b4\u03bf\u03b8\u03b7\u03bb\u03b9\u03b1\u03ba\u03ae \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1 \u2014 \u03ba\u03ac\u03c4\u03b9 \u03c0\u03bf\u03c5 \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03c3\u03b5\u03b9 \u03c4\u03bf \u03c3\u03c7\u03b7\u03bc\u03b1\u03c4\u03b9\u03c3\u03bc\u03cc \u03b1\u03b8\u03b7\u03c1\u03c9\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03c0\u03bb\u03b1\u03ba\u03ce\u03bd. 4.1 \u039a\u03bb\u03b9\u03bd\u03b9\u03ba\u03ac & \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ac \u03b4\u03b5\u03b4\u03bf\u03bc\u03ad\u03bd\u03b1<\/strong><\/p>\n\n\n\n \u039c\u03b9\u03b1 \u03c0\u03bf\u03bb\u03cd \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03cc\u03c4\u03b9 \u03c3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03bf\u03be\u03cd \u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1 (STEMI), \u03c5\u03c0\u03ac\u03c1\u03c7\u03b5\u03b9 \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7 \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u03c0\u03bf\u03c5 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03c5\u03bd butyrate \u03c3\u03c4\u03b1 \u03ba\u03cc\u03c0\u03c1\u03b1\u03bd\u03b1. \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b7 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 Differential implications of gut-related metabolites on outcomes between heart failure and myocardial infarction (European Journal of Preventive Cardiology) \u03b4\u03b5\u03af\u03c7\u03bd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03bf\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b5\u03c2 \u03b1\u03c0\u03cc \u03c4\u03b7\u03bd \u03c0\u03b7\u03b3\u03ae \u03c7\u03bf\u03bb\u03af\u03bd\u03b7\u03c2 \/ \u03ba\u03b1\u03c1\u03bd\u03b9\u03c4\u03af\u03bd\u03b7\u03c2 \u03c3\u03c5\u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03b5\u03c4\u03b9\u03ba\u03ac \u03bc\u03b5 \u03b5\u03c0\u03b1\u03bd\u03b1-\u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1 (reinfarction) \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 \u03c9\u03c2 \u03ad\u03ba\u03b2\u03b1\u03c3\u03b7 \u03bc\u03b5\u03c4\u03ac MI. \u03a4\u03bf butyrate \u03c6\u03b1\u03af\u03bd\u03b5\u03c4\u03b1\u03b9 \u03bd\u03b1 \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03cd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac \u03bc\u03b5\u03c4\u03ac MI \u03bc\u03ad\u03c3\u03c9 \u03b1\u03bd\u03b1\u03c3\u03c4\u03bf\u03bb\u03ae\u03c2 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03c9\u03b4\u03ce\u03bd \u03bf\u03b4\u03ce\u03bd, \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03b1\u03bd\u03c4\u03b9\u03bf\u03be\u03b5\u03b9\u03b4\u03c9\u03c4\u03b9\u03ba\u03ae\u03c2 \u03ac\u03bc\u03c5\u03bd\u03b1\u03c2 \u03ba\u03b1\u03b9 \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03b3\u03bf\u03bd\u03b9\u03b4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03ad\u03ba\u03c6\u03c1\u03b1\u03c3\u03b7\u03c2 (\u03bc\u03ad\u03c3\u03c9 epigenetics).<\/p>\n\n\n\n \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b7 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae \u03ba\u03b5\u03c4\u03bf\u03bd\u03b9\u03ba\u03ce\u03bd \u03c3\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd (\u03cc\u03c0\u03c9\u03c2 \u03b2-\u03c5\u03b4\u03c1\u03bf\u03be\u03c5\u03b2\u03bf\u03c5\u03c4\u03c5\u03c1\u03b9\u03ba\u03ae) \u03b1\u03c0\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ac \u03c3\u03c4\u03b5\u03bb\u03ad\u03c7\u03b7 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03b1\u03c1\u03ad\u03c7\u03b5\u03b9 \u201c\u03b5\u03bd\u03ad\u03c1\u03b3\u03b5\u03b9\u03b1 \u03ba\u03ac\u03bb\u03c5\u03c8\u03b7\u03c2\u201d \u03ae \u03b8\u03c1\u03b5\u03c0\u03c4\u03b9\u03ba\u03bf\u03cd\u03c2 \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ac \u03ba\u03cd\u03c4\u03c4\u03b1\u03c1\u03b1 \u03c3\u03b5 \u03c3\u03c5\u03bd\u03b8\u03ae\u03ba\u03b5\u03c2 stress \/ \u03c5\u03c0\u03bf-\u03b1\u03b9\u03bc\u03ac\u03c4\u03c9\u03c3\u03b7\u03c2.<\/p>\n\n\n\n \u03a4\u03ad\u03bb\u03bf\u03c2, \u03b7 \u03c1\u03cd\u03b8\u03bc\u03b9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03bf\u03b4\u03bf\u03cd TMA \u2192 TMAO \u03bc\u03b5\u03c4\u03ac MI \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03ad\u03c7\u03b5\u03b9 \u03c3\u03b7\u03bc\u03b1\u03c3\u03af\u03b1 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03bc\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b1 \u03c0\u03c1\u03cc\u03b3\u03bd\u03c9\u03c3\u03b7, \u03bc\u03b5\u03b9\u03ce\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03c0\u03b1\u03bd\u03b1\u03b5\u03bc\u03c6\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03bf\u03c2 \u03ae \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2.<\/p>\n\n\n\n \u03a0\u03c1\u03bf\u03bb\u03b7\u03c0\u03c4\u03b9\u03ba\u03ac (\u03c0\u03c1\u03b9\u03bd MI): \u0397 \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd (\u03c0.\u03c7. \u03c3\u03c4\u03b5\u03bb\u03b5\u03c7\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b5\u03bd\u03b9\u03c3\u03c7\u03cd\u03bf\u03c5\u03bd \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 SCFAs) \u03ba\u03b1\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd (\u03cc\u03c0\u03c9\u03c2 butyrate) \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03b5\u03b9 \u03c4\u03bf \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03c6\u03bf\u03c1\u03c4\u03af\u03bf \u03bc\u03ad\u03c3\u03c9 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7\u03c2 TMAO, \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae\u03c2 \u03ba\u03b1\u03b9 \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7\u03c2 \u03b5\u03bd\u03b4\u03bf\u03b8\u03b7\u03bb\u03af\u03bf\u03c5.<\/p>\n\n\n\n \u039c\u03b5\u03c4\u03ac \u03c4\u03bf \u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1: \u0397 \u03b1\u03bd\u03ac\u03c0\u03c4\u03c5\u03be\u03b7 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03c5\u03c4\u03b9\u03ba\u03ce\u03bd \u03c3\u03c4\u03c1\u03b1\u03c4\u03b7\u03b3\u03b9\u03ba\u03ce\u03bd \u03c0\u03bf\u03c5 \u03b2\u03b1\u03c3\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03b5 \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 butyrate \u03ae \u03ba\u03b5\u03c4\u03bf\u03bd\u03ce\u03bd (\u03bc\u03b5\u03c4\u03b1\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ac) \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c5\u03c0\u03bf\u03c3\u03c7\u03cc\u03bc\u03b5\u03bd\u03b7 \u03ba\u03b1\u03c4\u03b5\u03cd\u03b8\u03c5\u03bd\u03c3\u03b7. \u039c\u03b1\u03ba\u03c1\u03bf\u03c7\u03c1\u03cc\u03bd\u03b9\u03b5\u03c2 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ad\u03c2 \u03b5\u03af\u03bd\u03b1\u03b9 \u03b1\u03c0\u03b1\u03c1\u03b1\u03af\u03c4\u03b7\u03c4\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03bd\u03b1 \u03b1\u03be\u03b9\u03bf\u03bb\u03bf\u03b3\u03b7\u03b8\u03b5\u03af \u03b7 \u03b1\u03c3\u03c6\u03ac\u03bb\u03b5\u03b9\u03b1, \u03c4\u03bf \u03ba\u03b1\u03c4\u03ac\u03bb\u03bb\u03b7\u03bb\u03bf \u03c3\u03ba\u03b5\u03cd\u03b1\u03c3\u03bc\u03b1, \u03b7 \u03b4\u03bf\u03c3\u03bf\u03bb\u03bf\u03b3\u03af\u03b1 \u03ba\u03b1\u03b9 \u03b7 \u03c7\u03c1\u03bf\u03bd\u03b9\u03ba\u03ae \u03c7\u03bf\u03c1\u03ae\u03b3\u03b7\u03c3\u03b7.<\/p>\n\n\n\n \u0397 ** \u03b5\u03be\u03b1\u03c4\u03bf\u03bc\u03b9\u03ba\u03b5\u03c5\u03bc\u03ad\u03bd\u03b7 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae \u03b9\u03b1\u03c4\u03c1\u03b9\u03ba\u03ae** (\u201cprecision microbiome medicine\u201d) \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c4\u03bf \u03bc\u03ad\u03bb\u03bb\u03bf\u03bd: \u03b1\u03bd\u03ac\u03bb\u03bf\u03b3\u03b1 \u03bc\u03b5 \u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03cc \u03c0\u03c1\u03bf\u03c6\u03af\u03bb \u03b5\u03bd\u03cc\u03c2 \u03b1\u03c4\u03cc\u03bc\u03bf\u03c5 (\u03c0.\u03c7. \u03c0\u03bf\u03b9\u03ba\u03b9\u03bb\u03cc\u03c4\u03b7\u03c4\u03b1, \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1 \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1, \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b5\u03c2), \u03bd\u03b1 \u03c3\u03c7\u03b5\u03b4\u03b9\u03ac\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03bc\u03ad\u03bd\u03b5\u03c2 \u03c0\u03b1\u03c1\u03b5\u03bc\u03b2\u03ac\u03c3\u03b5\u03b9\u03c2 (\u03c0\u03c1\u03bf\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ac, postbiotics \u03ae \u03b4\u03b9\u03b1\u03c4\u03c1\u03bf\u03c6\u03b9\u03ba\u03ad\u03c2 \u03c0\u03c1\u03bf\u03c3\u03b1\u03c1\u03bc\u03bf\u03b3\u03ad\u03c2).<\/p>\n\n\n\n \u03a3\u03c5\u03bc\u03c0\u03b5\u03c1\u03ac\u03c3\u03bc\u03b1\u03c4\u03b1<\/strong><\/p>\n\n\n\n \u03a4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03ad\u03c1\u03bf\u03c5 \u03c3\u03c5\u03bd\u03b4\u03ad\u03b5\u03c4\u03b1\u03b9 \u03c3\u03c4\u03b5\u03bd\u03ac \u03bc\u03b5 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ac \u03bd\u03bf\u03c3\u03ae\u03bc\u03b1\u03c4\u03b1 \u03c0\u03c1\u03b9\u03bd \u03b1\u03c0\u03cc \u03c4\u03bf \u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1, \u03bc\u03ad\u03c3\u03c9 \u03bc\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03ce\u03bd \u03c0\u03bf\u03c5 \u03c0\u03b5\u03c1\u03b9\u03bb\u03b1\u03bc\u03b2\u03ac\u03bd\u03bf\u03c5\u03bd \u03c4\u03bf TMAO, \u03c4\u03b7 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03ba\u03b1\u03b9 \u03c4\u03b7 \u03b4\u03b9\u03b1\u03c4\u03b1\u03c1\u03b1\u03c7\u03ae \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd \u03c6\u03c1\u03b1\u03b3\u03bc\u03bf\u03cd.<\/p>\n\n\n\n \u039c\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b5\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bd, \u03cc\u03c0\u03c9\u03c2 \u03c4\u03b1 SCFAs (\u03b9\u03b4\u03b9\u03b1\u03af\u03c4\u03b5\u03c1\u03b1 \u03c4\u03bf butyrate), \u03ad\u03c7\u03bf\u03c5\u03bd \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c4\u03b5\u03c5\u03c4\u03b9\u03ba\u03cc \u03c1\u03cc\u03bb\u03bf \u03ba\u03b1\u03b9 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03bc\u03b5\u03b9\u03ce\u03c3\u03bf\u03c5\u03bd \u03c4\u03bf\u03bd \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03cc \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf.<\/p>\n\n\n\n \u039c\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc \u03bf\u03be\u03cd \u03ad\u03bc\u03c6\u03c1\u03b1\u03b3\u03bc\u03b1, \u03b7 \u03b5\u03bd\u03af\u03c3\u03c7\u03c5\u03c3\u03b7 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bd \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 butyrate \u03ae \u03b7 \u03c7\u03c1\u03ae\u03c3\u03b7 \u03bc\u03b5\u03c4\u03b1\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b2\u03bf\u03b7\u03b8\u03ae\u03c3\u03b5\u03b9 \u03c3\u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03ba\u03b1\u03bc\u03c8\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03ac\u03c2 \u03ba\u03b1\u03b9 \u03bd\u03b1 \u03c0\u03b5\u03c1\u03b9\u03bf\u03c1\u03af\u03c3\u03b5\u03b9 \u03c4\u03b9\u03c2 \u03b5\u03c0\u03b9\u03c0\u03bb\u03bf\u03ba\u03ad\u03c2 (\u03cc\u03c0\u03c9\u03c2 \u03b5\u03c0\u03b1\u03bd\u03b5\u03bc\u03c6\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03b1 \u03ae \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1).<\/p>\n\n\n\n \u03a0\u03b1\u03c1\u03ac \u03c4\u03b9\u03c2 \u03c5\u03c0\u03bf\u03c3\u03c7\u03cc\u03bc\u03b5\u03bd\u03b5\u03c2 \u03c0\u03c1\u03bf\u03bf\u03c0\u03c4\u03b9\u03ba\u03ad\u03c2, \u03b1\u03c0\u03b1\u03b9\u03c4\u03bf\u03cd\u03bd\u03c4\u03b1\u03b9 \u03ba\u03bb\u03b9\u03bd\u03b9\u03ba\u03ad\u03c2 \u03b4\u03bf\u03ba\u03b9\u03bc\u03ad\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03b7 \u03bc\u03b5\u03c4\u03ac\u03c6\u03c1\u03b1\u03c3\u03b7 \u03c4\u03c9\u03bd \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03b9\u03ba\u03ce\u03bd \u03b5\u03c5\u03c1\u03b7\u03bc\u03ac\u03c4\u03c9\u03bd \u03c3\u03b5 \u03b1\u03c3\u03c6\u03b1\u03bb\u03b5\u03af\u03c2 \u03ba\u03b1\u03b9 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03c3\u03bc\u03b1\u03c4\u03b9\u03ba\u03ad\u03c2 \u03b8\u03b5\u03c1\u03b1\u03c0\u03b5\u03af\u03b5\u03c2 \u03b3\u03b9\u03b1 \u03c4\u03bf\u03c5\u03c2 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2.<\/p>\n\n\n\n \u0392\u03b9\u03b2\u03bb\u03b9\u03bf\u03b3\u03c1\u03b1\u03c6\u03af\u03b1 \u0395\u03c0\u03b9\u03bb\u03b5\u03b3\u03bc\u03ad\u03bd\u03c9\u03bd \u039c\u03b5\u03bb\u03b5\u03c4\u03ce\u03bd<\/p>\n\n\n\n Differential implications of gut-related metabolites on outcomes between heart failure and myocardial infarction, European Journal of Preventive Cardiology. Changes of gut microbiome composition and metabolites associated with hypertensive heart failure rats, BMC Microbiology. Gut Microbiota and Metabolic Alterations Associated with Heart Failure and Coronary Artery Disease, MDPI \/ International \u2026. Update on gut microbiota in cardiovascular diseases, \u03b1\u03bd\u03b1\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7 PubMed. Gut Microbiota and Cardiovascular Diseases: Unravelling the Role of Dysbiosis and Microbial Metabolites, PubMed. Microbiome-derived links between gut microbiome and cardiovascular disease, Microbiome (2024). The gut-heart connection: how the microbiome influences cardiovascular health, International Journal of Biological & Pharmaceutical Sciences, 2025. The gut-heart axis: a review of gut microbiota, CVD mechanisms and emerging therapies, Review Article, JRCD. \u039f \u03ac\u03be\u03bf\u03bd\u03b1\u03c2 \u03ad\u03bd\u03c4\u03b5\u03c1\u03bf\u2013\u03ba\u03b1\u03c1\u03b4\u03b9\u03ac (gut\u2013heart axis) \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03c0\u03b5\u03b4\u03af\u03bf \u03c1\u03b1\u03b3\u03b4\u03b1\u03af\u03b1\u03c2 \u03ad\u03c1\u03b5\u03c5\u03bd\u03b1\u03c2 \u03c4\u03b1 \u03c4\u03b5\u03bb\u03b5\u03c5\u03c4\u03b1\u03af\u03b1 \u03c7\u03c1\u03cc\u03bd\u03b9\u03b1. \u03a0\u03bb\u03ad\u03bf\u03bd \u03b3\u03bd\u03c9\u03c1\u03af\u03b6\u03bf\u03c5\u03bc\u03b5 \u03cc\u03c4\u03b9 \u03c4\u03bf \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03cc \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1…<\/p>\n","protected":false},"author":1,"featured_media":4245,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[50],"tags":[],"class_list":["post-4244","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-private-label"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=\/wp\/v2\/posts\/4244","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4244"}],"version-history":[{"count":1,"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=\/wp\/v2\/posts\/4244\/revisions"}],"predecessor-version":[{"id":4246,"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=\/wp\/v2\/posts\/4244\/revisions\/4246"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=\/wp\/v2\/media\/4245"}],"wp:attachment":[{"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4244"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4244"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/swiss-formula.gr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4244"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\u0397 \u03bc\u03b5\u03c4\u03b1-\u03b1\u03bd\u03ac\u03bb\u03c5\u03c3\u03b7 \u03b1\u03c0\u03cc \u03c4\u03b7 MDPI \u03b1\u03bd\u03b1\u03b4\u03b5\u03b9\u03ba\u03bd\u03cd\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03c5\u03c8\u03b7\u03bb\u03ac \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 TMAO \u2014 \u03ad\u03bd\u03b1\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03cc\u03c2 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b7\u03c2 \u03c0\u03bf\u03c5 \u03c0\u03c1\u03bf\u03ad\u03c1\u03c7\u03b5\u03c4\u03b1\u03b9 \u03b1\u03c0\u03cc \u03c7\u03bf\u03bb\u03af\u03bd\u03b7 \u03ae \u03ba\u03b1\u03c1\u03bd\u03b9\u03c4\u03af\u03bd\u03b7 \u2014 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b3\u03b9\u03b1 \u201cmajor adverse cardiovascular events\u201d (MACE) \u03ba\u03b1\u03b9 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7.
\u03a4\u03bf TMAO \u03ad\u03c7\u03b5\u03b9 \u03b5\u03c0\u03af\u03c3\u03b7\u03c2 \u03b1\u03c0\u03bf\u03b4\u03b5\u03b9\u03c7\u03b8\u03b5\u03af \u03cc\u03c4\u03b9 \u03b5\u03c0\u03b9\u03b4\u03c1\u03ac \u03c3\u03c4\u03b7\u03bd \u03b1\u03b8\u03b7\u03c1\u03bf\u03c3\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7: \u03c0\u03c1\u03bf\u03ac\u03b3\u03b5\u03b9 \u03c4\u03b7 \u03c3\u03c5\u03c3\u03c3\u03ce\u03c1\u03b5\u03c5\u03c3\u03b7 \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7\u03c2, \u03bc\u03b5\u03b9\u03ce\u03bd\u03b5\u03b9 \u03c4\u03bf\u03bd \u03b1\u03bd\u03c4\u03af\u03c3\u03c4\u03c1\u03bf\u03c6\u03bf \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc \u03c7\u03bf\u03bb\u03b7\u03c3\u03c4\u03b5\u03c1\u03cc\u03bb\u03b7\u03c2, \u03b4\u03b9\u03b5\u03b3\u03b5\u03af\u03c1\u03b5\u03b9 \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae \u03c3\u03c4\u03bf \u03b5\u03bd\u03b4\u03bf\u03b8\u03ae\u03bb\u03b9\u03bf \u03ba\u03b1\u03b9 \u03b1\u03c5\u03be\u03ac\u03bd\u03b5\u03b9 \u03c4\u03b7\u03bd \u03b5\u03bd\u03b5\u03c1\u03b3\u03bf\u03c0\u03bf\u03af\u03b7\u03c3\u03b7 \u03b1\u03b9\u03bc\u03bf\u03c0\u03b5\u03c4\u03b1\u03bb\u03af\u03c9\u03bd.
journals.lww.com\u03a3\u03b5 \u03b1\u03c3\u03b8\u03b5\u03bd\u03b5\u03af\u03c2 \u03bc\u03b5 \u03c3\u03c4\u03b5\u03c6\u03b1\u03bd\u03b9\u03b1\u03af\u03b1 \u03bd\u03cc\u03c3\u03bf (CAD) \u03ba\u03b1\u03b9 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1 (HFrEF), \u03bc\u03b9\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03ad\u03b4\u03b5\u03b9\u03be\u03b5 \u03b1\u03c5\u03be\u03b7\u03bc\u03ad\u03bd\u03bf \u03bb\u03cc\u03b3\u03bf Bacillota \/ Bacteroidota \u03c3\u03c4\u03bf \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03af\u03c9\u03bc\u03b1, \u03ba\u03b1\u03b8\u03ce\u03c2 \u03ba\u03b1\u03b9 \u03b4\u03b9\u03b1\u03c6\u03bf\u03c1\u03ad\u03c2 \u03c3\u03c4\u03b7 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03ae \u03c3\u03cd\u03bd\u03b8\u03b5\u03c3\u03b7 \u03c0\u03bf\u03c5 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03ad\u03c2 \u03c3\u03c4\u03bf \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03c3\u03bc\u03cc.
PubMed \u0395\u03c0\u03b9\u03c0\u03bb\u03ad\u03bf\u03bd, \u03b7 \u03b1\u03bd\u03b1\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7 \u201cUpdate on gut microbiota in cardiovascular diseases\u201d \u03c0\u03b5\u03c1\u03b9\u03b3\u03c1\u03ac\u03c6\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b5\u03ba\u03c4\u03cc\u03c2 \u03b1\u03c0\u03cc \u03c4\u03bf TMAO, \u03ba\u03b1\u03b9 \u03ac\u03bb\u03bb\u03b1 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03b9\u03ba\u03ac \u03c0\u03c1\u03bf\u03ca\u03cc\u03bd\u03c4\u03b1 \u03c4\u03c9\u03bd \u03b2\u03b1\u03ba\u03c4\u03b7\u03c1\u03af\u03c9\u03bd \u2014 \u03cc\u03c0\u03c9\u03c2 SCFAs (\u03bf\u03bb\u03b9\u03b3\u03bf\u03ac\u03bb\u03c5\u03c4\u03b1 \u03bb\u03b9\u03c0\u03b1\u03c1\u03ac \u03bf\u03be\u03ad\u03b1) \u03ba\u03b1\u03b9 \u03c7\u03bf\u03bb\u03b9\u03ba\u03ac \u03bf\u03be\u03ad\u03b1 \u2014 \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03bc\u03b5 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ad\u03c2 \u03c0\u03b1\u03b8\u03ae\u03c3\u03b5\u03b9\u03c2.
PubMed \u0397 \u03b1\u03bd\u03b9\u03c3\u03bf\u03c1\u03c1\u03bf\u03c0\u03af\u03b1 \u03c4\u03bf\u03c5 \u03b5\u03bd\u03c4\u03b5\u03c1\u03b9\u03ba\u03bf\u03cd \u03c6\u03c1\u03b1\u03b3\u03bc\u03bf\u03cd (\u201cleaky gut\u201d), \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03c0\u03c1\u03bf\u03ba\u03bb\u03b7\u03b8\u03b5\u03af \u03b1\u03c0\u03cc \u03b4\u03c5\u03c3\u03b2\u03af\u03c9\u03c3\u03b7, \u03bf\u03b4\u03b7\u03b3\u03b5\u03af \u03c3\u03b5 \u03c3\u03c5\u03c3\u03c4\u03b7\u03bc\u03b1\u03c4\u03b9\u03ba\u03ae \u03c6\u03bb\u03b5\u03b3\u03bc\u03bf\u03bd\u03ae, \u03b7 \u03bf\u03c0\u03bf\u03af\u03b1 \u03b1\u03c0\u03bf\u03c4\u03b5\u03bb\u03b5\u03af \u03b2\u03b1\u03c3\u03b9\u03ba\u03cc \u03b5\u03c0\u03b9\u03b2\u03b1\u03c1\u03c5\u03bd\u03c4\u03b9\u03ba\u03cc \u03c0\u03b1\u03c1\u03ac\u03b3\u03bf\u03bd\u03c4\u03b1 \u03b3\u03b9\u03b1 \u03b1\u03b8\u03b7\u03c1\u03bf\u03c3\u03ba\u03bb\u03ae\u03c1\u03c9\u03c3\u03b7 \u03ba\u03b1\u03b9 \u03c5\u03c0\u03ad\u03c1\u03c4\u03b1\u03c3\u03b7.
journals.lww.com \u0397 \u03ba\u03c1\u03b9\u03c4\u03b9\u03ba\u03ae \u03b1\u03bd\u03b1\u03c3\u03ba\u03cc\u03c0\u03b7\u03c3\u03b7 \u201cMicrobiota-derived Trimethylamine N-oxide Predicts Cardiovascular Risk\u201d \u03c5\u03c0\u03bf\u03b3\u03c1\u03b1\u03bc\u03bc\u03af\u03b6\u03b5\u03b9 \u03cc\u03c4\u03b9 \u03b1\u03ba\u03cc\u03bc\u03b7 \u03ba\u03b1\u03b9 \u03c3\u03b5 \u03c3\u03c4\u03b1\u03b8\u03b5\u03c1\u03ae \u03c3\u03c4\u03b5\u03c6\u03b1\u03bd\u03b9\u03b1\u03af\u03b1 \u03bd\u03cc\u03c3\u03bf, \u03c4\u03b1 \u03b5\u03c0\u03af\u03c0\u03b5\u03b4\u03b1 TMAO \u03bc\u03c0\u03bf\u03c1\u03b5\u03af \u03bd\u03b1 \u03b5\u03af\u03bd\u03b1\u03b9 \u03c0\u03c1\u03bf\u03b3\u03bd\u03c9\u03c3\u03c4\u03b9\u03ba\u03ac \u03b3\u03b9\u03b1 \u03b4\u03c5\u03c3\u03bc\u03b5\u03bd\u03b5\u03af\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03b3\u03b3\u03b5\u03b9\u03b1\u03ba\u03ad\u03c2 \u03b5\u03be\u03b5\u03bb\u03af\u03be\u03b5\u03b9\u03c2.
MDPI <\/p>\n\n\n\n
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3.2 \u039c\u03b5\u03c4\u03b1\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ac (postbiotics)<\/strong><\/p>\n\n\n\n
\u0395\u03c0\u03af\u03c3\u03b7\u03c2, \u03bc\u03ad\u03c3\u03c9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd, \u03b8\u03b1 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03c3\u03b5 \u03bd\u03b1 \u03c3\u03c4\u03bf\u03c7\u03b5\u03c5\u03c4\u03b5\u03af \u03b7 \u03bc\u03b5\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03c0\u03b1\u03c1\u03b1\u03b3\u03c9\u03b3\u03ae\u03c2 TMA \u2192 TMAO, \u03c0\u03c1\u03bf\u03c3\u03c6\u03ad\u03c1\u03bf\u03bd\u03c4\u03b1\u03c2 \u03ad\u03bd\u03b1\u03bd \u03ad\u03bc\u03bc\u03b5\u03c3\u03bf \u03c4\u03c1\u03cc\u03c0\u03bf \u03c0\u03c1\u03cc\u03bb\u03b7\u03c8\u03b7\u03c2 \u03c4\u03b7\u03c2 \u03c0\u03c1\u03bf-\u03b1\u03b8\u03b7\u03c1\u03bf\u03b3\u03ad\u03bd\u03b5\u03c3\u03b7\u03c2.<\/strong><\/p>\n\n\n\n\n
<\/li>\n<\/ol>\n\n\n\n
\u03a3\u03b5 \u03c0\u03b5\u03b9\u03c1\u03b1\u03bc\u03b1\u03c4\u03cc\u03b6\u03c9\u03b1 (\u03c0\u03bf\u03bd\u03c4\u03af\u03ba\u03b9\u03b1 \u03c7\u03c9\u03c1\u03af\u03c2 \u03bc\u03b9\u03ba\u03c1\u03bf\u03c7\u03bb\u03c9\u03c1\u03af\u03b4\u03b1) \u03c0\u03bf\u03c5 \u03bc\u03b5\u03c4\u03b1\u03bc\u03bf\u03c3\u03c7\u03b5\u03cd\u03b8\u03b7\u03ba\u03b1\u03bd \u03bc\u03b5 \u03b1\u03c5\u03c4\u03ac \u03c4\u03b1 \u03b2\u03b1\u03ba\u03c4\u03ae\u03c1\u03b9\u03b1, \u03c0\u03b1\u03c1\u03b1\u03c4\u03b7\u03c1\u03ae\u03b8\u03b7\u03ba\u03b5 \u03b1\u03cd\u03be\u03b7\u03c3\u03b7 \u03c3\u03c4\u03b7\u03bd \u03b2-\u03c5\u03b4\u03c1\u03bf\u03be\u03c5\u03b2\u03bf\u03c5\u03c4\u03c5\u03c1\u03b9\u03ba\u03ae (\u03b2-hydroxybutyrate) \u03ba\u03b1\u03b9 \u03b2\u03b5\u03bb\u03c4\u03af\u03c9\u03c3\u03b7 \u03c4\u03b7\u03c2 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03bb\u03b5\u03b9\u03c4\u03bf\u03c5\u03c1\u03b3\u03af\u03b1\u03c2 \u03bc\u03b5\u03c4\u03ac \u03b1\u03c0\u03cc MI, \u03b4\u03b5\u03af\u03c7\u03bd\u03bf\u03bd\u03c4\u03b1\u03c2 \u03cc\u03c4\u03b9 \u03bf\u03b9 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03b1\u03ba\u03bf\u03af \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b5\u03c2 \u03bc\u03c0\u03bf\u03c1\u03bf\u03cd\u03bd \u03bd\u03b1 \u03c5\u03c0\u03bf\u03c3\u03c4\u03b7\u03c1\u03af\u03be\u03bf\u03c5\u03bd \u03c4\u03b7\u03bd \u03b1\u03bd\u03ac\u03ba\u03b1\u03bc\u03c8\u03b7.<\/p>\n\n\n\n
\u03a0\u03b9\u03bf \u03c3\u03c5\u03b3\u03ba\u03b5\u03ba\u03c1\u03b9\u03bc\u03ad\u03bd\u03b1: \u03c3\u03c4\u03b7\u03bd \u03af\u03b4\u03b9\u03b1 \u03bc\u03b5\u03bb\u03ad\u03c4\u03b7 \u03bf\u03b9 \u03c3\u03c5\u03b3\u03b3\u03c1\u03b1\u03c6\u03b5\u03af\u03c2 \u03b1\u03bd\u03b1\u03c6\u03ad\u03c1\u03bf\u03c5\u03bd \u03cc\u03c4\u03b9 \u03b7 \u03c0\u03bf\u03c1\u03b5\u03af\u03b1 \u03c4\u03b7\u03c2 \u03bf\u03b4\u03bf\u03cd carnitine \u2192 TMAO \u03ae\u03c4\u03b1\u03bd \u03c0\u03b9\u03bf \u03c3\u03b7\u03bc\u03b1\u03bd\u03c4\u03b9\u03ba\u03ae \u03b3\u03b9\u03b1 \u03c4\u03b7\u03bd \u03c0\u03c1\u03cc\u03b2\u03bb\u03b5\u03c8\u03b7 \u03ba\u03b1\u03c1\u03b4\u03b9\u03b1\u03ba\u03ae\u03c2 \u03b1\u03bd\u03b5\u03c0\u03ac\u03c1\u03ba\u03b5\u03b9\u03b1\u03c2 \u03bc\u03b5\u03c4\u03ac MI, \u03b5\u03bd\u03ce \u03ac\u03bb\u03bb\u03bf\u03b9 \u03bc\u03b5\u03c4\u03b1\u03b2\u03bf\u03bb\u03af\u03c4\u03b5\u03c2 \u03cc\u03c0\u03c9\u03c2 \u03b7 \u03b2\u03ae\u03c4\u03b1\u03ca\u03bd\u03b7 (betaine) \u03c3\u03c7\u03b5\u03c4\u03af\u03b6\u03bf\u03bd\u03c4\u03b1\u03b9 \u03c0\u03b9\u03bf \u03c0\u03bf\u03bb\u03cd \u03bc\u03b5 \u03c4\u03bf\u03bd \u03ba\u03af\u03bd\u03b4\u03c5\u03bd\u03bf \u03b5\u03c0\u03b1\u03bd\u03b5\u03bc\u03c6\u03c1\u03ac\u03b3\u03bc\u03b1\u03c4\u03bf\u03c2.<\/p>\n\n\n\n
4.2 \u039c\u03b7\u03c7\u03b1\u03bd\u03b9\u03c3\u03bc\u03bf\u03af \u03c0\u03c1\u03bf\u03c3\u03c4\u03b1\u03c3\u03af\u03b1\u03c2 \u03bc\u03ad\u03c3\u03c9 \u03bc\u03b9\u03ba\u03c1\u03bf\u03b2\u03b9\u03c9\u03bc\u03ac\u03c4\u03c9\u03bd \/ \u03bc\u03b5\u03c4\u03b1\u03b2\u03b9\u03bf\u03c4\u03b9\u03ba\u03ce\u03bd<\/strong><\/p>\n\n\n\n\n
OUP Academic<\/p>\n\n\n\n
BioMed Central<\/p>\n\n\n\n
MDPI
+1<\/p>\n\n\n\n
PubMed<\/p>\n\n\n\n
PubMed<\/p>\n\n\n\n
BioMed Central<\/p>\n\n\n\n
ijbpsa.com<\/p>\n\n\n\n
Journal of Rare Cardiovascular Diseases<\/p>\n","protected":false},"excerpt":{"rendered":"